Active resolution of inflammation: No evidence that specialized lipid messengers are involved

[Joachim]

Inflammation is the result of an active defense reaction by our immune system. It mostly disappears by itself. It was once assumed to be a passive process because the immune cells involved, having done their work, gradually die off or migrate. Today, we know that our body also actively controls the resolution of inflammation. To this end, certain cells of the innate immune system, known as M1 macrophages, which are pro-inflammatory and in the first instance serve as a defense mechanism, transform into M2 macrophages, which are anti-inflammatory and primarily help to heal wounds.

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