Complex relationships between bacteria and markers of lower airway infection and inflammation in cystic fibrosis

[Joachim]

The lower airways of patients with cystic fibrosis (CF) have unique biochemical features that correlate with the complex communities of lung bacteria typical of this disease, according to a multicenter study led by researchers from Ann & Robert H. Lurie Children's Hospital of Chicago. These findings offer insights into the underlying biological mechanisms driving infection and inflammation in the CF lungs, and may help develop novel targeted therapies and more precise diagnostics to improve the care of children with CF. Results were published in the journal Frontiers of Cellular and Infection Microbiology.

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