Successful murine model of dermatomyositis reveals underlying immune system involvement

[Joachim]

Some diseases involve autoimmune reactions when the body begins to attack its own cells and proteins. The biological mechanisms underlying these diseases are often unknown, making treatment challenging. Now, a group at TMDU has created a murine model for a disease known as "anti-MDA5 antibody-positive dermatomyositis." The use of this model has allowed them to identify components of the immune system that are vital in disease development, with implications for future treatments.

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